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FEZF2

GENERAL INFORMATION

Gene name

 FEZF2

Gene description

 FEZ family zinc finger 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (glioma)
HPA (cell line):Cell line enhanced (AF22, NTERA-2)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (glioma)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 FEZF2 (HGNC Symbol)

Synonyms

 FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312

Description

 FEZ family zinc finger 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p14.2

Chromosome location (bp)

 62369681 - 62374324

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000153266 (version 83.38)

Entrez gene

 55079

UniProt

 Q8TBJ5 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8TBJ5

Antibodypedia

 FEZF2 antibodies

PROTEIN BROWSER
FEZF2-001
FEZF2-002
FEZF2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FEZF2-001
ENSP00000283268
ENST00000283268
Q8TBJ5 [Direct mapping]
Fez family zinc finger protein 2
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003682 [chromatin binding]
GO:0005634 [nucleus]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007411 [axon guidance]
GO:0007413 [axonal fasciculation]
GO:0007626 [locomotory behavior]
GO:0008285 [negative regulation of cell proliferation]
GO:0016358 [dendrite development]
GO:0021537 [telencephalon development]
GO:0021542 [dentate gyrus development]
GO:0021797 [forebrain anterior/posterior pattern specification]
GO:0021853 [cerebral cortex GABAergic interneuron migration]
GO:0021895 [cerebral cortex neuron differentiation]
GO:0021902 [commitment of neuronal cell to specific neuron type in forebrain]
GO:0030900 [forebrain development]
GO:0045665 [negative regulation of neuron differentiation]
GO:0045666 [positive regulation of neuron differentiation]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0048664 [neuron fate determination]
GO:1902667 [regulation of axon guidance]
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 459 aa
48.8 kDa 		No 0
FEZF2-002
ENSP00000418804
ENST00000475839
Q8TBJ5 [Direct mapping]
Fez family zinc finger protein 2
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0005634 [nucleus]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007411 [axon guidance]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 459 aa
48.8 kDa 		No 0
FEZF2-004
ENSP00000418589
ENST00000486811
Q8TBJ5 [Direct mapping]
Fez family zinc finger protein 2
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0005634 [nucleus]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007411 [axon guidance]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 459 aa
48.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.