Cell atlas - TGIF2LX - The Human Protein Atlas

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TGIF2LX

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TGIF2LX
Gene description	TGFB-induced factor homeobox 2-like, X-linked
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Group enriched (U-266/84, U-2 OS, SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA034543
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (U-266/84, U-2 OS, SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA034543	SH-SY5Y	Nucleoplasm	Intensity
	HPA034543	U-2 OS	Nucleoplasm	Intensity

GENE INFORMATION
Gene name	TGIF2LX
Synonyms
Description	TGFB-induced factor homeobox 2-like, X-linked (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the TALE/TGIF homeobox family of transcription factors. Testis-specific expression suggests that this gene may play a role in spermatogenesis. A homolog of this gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q21.31
Chromosome location (bp)	89921882 - 89922883
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153779 (version 83.38)
Entrez gene	90316
UniProt	Q8IUE1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IUE1
Antibodypedia	TGIF2LX antibodies

PROTEIN BROWSER

TGIF2LX-001	TGIF2LX-002	TGIF2LX-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TGIF2LX-001 ENSP00000355119 ENST00000283891	Q8IUE1 [Direct mapping] Homeobox protein TGIF2LX Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	241 aa 26.7 kDa	No	0
TGIF2LX-002 ENSP00000453704 ENST00000561129	Q8IUE1 [Direct mapping] Homeobox protein TGIF2LX Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	241 aa 26.7 kDa	No	0
TGIF2LX-201 ENSP00000481303 ENST00000622167	A0A087WXU6 [Direct mapping] Homeobox protein TGIF2LX Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] Show all	185 aa 20.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.