Fields »
ABOUT
HELP
BLOG
CEBPG

GENERAL INFORMATION

Gene name

 CEBPG

Gene description

 CCAAT/enhancer binding protein (C/EBP), gamma

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA012024
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable) and renal cancer (unfavourable).
Endometrial cancer p<0.001
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA012024

GENE INFORMATION

Gene name

 CEBPG (HGNC Symbol)

Synonyms

 GPE1BP, IG/EBP-1

Description

 CCAAT/enhancer binding protein (C/EBP), gamma (HGNC Symbol)

Entrez gene summary

 The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]

Chromosome

 19

Cytoband

 q13.11

Chromosome location (bp)

 33373330 - 33382686

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000153879 (version 83.38)

Entrez gene

 1054

UniProt

 P53567 (UniProt - Evidence at protein level)

neXtProt

 NX_P53567

Antibodypedia

 CEBPG antibodies

PROTEIN BROWSER
CEBPG-001
CEBPG-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CEBPG-001
ENSP00000284000
ENST00000284000
P53567 [Direct mapping]
CCAAT/enhancer-binding protein gamma
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001889 [liver development]
GO:0003677 [DNA binding]
GO:0003690 [double-stranded DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006955 [immune response]
GO:0008134 [transcription factor binding]
GO:0016071 [mRNA metabolic process]
GO:0030183 [B cell differentiation]
GO:0042267 [natural killer cell mediated cytotoxicity]
GO:0043353 [enucleate erythrocyte differentiation]
GO:0043388 [positive regulation of DNA binding]
GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity]
GO:0043565 [sequence-specific DNA binding]
GO:0044377 [RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending]
GO:0045078 [positive regulation of interferon-gamma biosynthetic process]
GO:0045739 [positive regulation of DNA repair]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
Show all
 150 aa
16.4 kDa 		No 0
CEBPG-002
ENSP00000466022
ENST00000585933
P53567 [Direct mapping]
CCAAT/enhancer-binding protein gamma
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001889 [liver development]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006955 [immune response]
GO:0008134 [transcription factor binding]
GO:0030183 [B cell differentiation]
GO:0042267 [natural killer cell mediated cytotoxicity]
GO:0043353 [enucleate erythrocyte differentiation]
GO:0043388 [positive regulation of DNA binding]
GO:0043433 [negative regulation of sequence-specific DNA binding transcription factor activity]
GO:0043565 [sequence-specific DNA binding]
GO:0045078 [positive regulation of interferon-gamma biosynthetic process]
GO:0045739 [positive regulation of DNA repair]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0051091 [positive regulation of sequence-specific DNA binding transcription factor activity]
Show all
 150 aa
16.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.