Cell atlas - CHST9 - The Human Protein Atlas

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CHST9

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CHST9
Gene description	Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (RPTEC TERT1, SCLC-21H, Hep G2, CACO-2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (RPTEC TERT1, SCLC-21H, Hep G2, CACO-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CHST9 (HGNC Symbol)
Synonyms	GALNAC-4-ST2, GALNAC4ST-2
Description	Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]
Chromosome	18
Cytoband	q11.2
Chromosome location (bp)	26906481 - 27185317
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154080 (version 83.38)
Entrez gene	83539
UniProt	Q7L1S5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7L1S5
Antibodypedia	CHST9 antibodies

PROTEIN BROWSER

CHST9-001	CHST9-002	CHST9-003	CHST9-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CHST9-001 ENSP00000480991 ENST00000618847	Q7L1S5 [Direct mapping] Carbohydrate sulfotransferase 9 A0A024RC28 [Target identity:100%; Query identity:100%] Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9, isoform CRA_b Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001537 [N-acetylgalactosamine 4-O-sulfotransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008146 [sulfotransferase activity] GO:0016021 [integral component of membrane] GO:0016051 [carbohydrate biosynthetic process] GO:0030166 [proteoglycan biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0030204 [chondroitin sulfate metabolic process] GO:0030206 [chondroitin sulfate biosynthetic process] GO:0042446 [hormone biosynthetic process] GO:0044281 [small molecule metabolic process] Show all	443 aa 52.1 kDa	No	0
CHST9-002 ENSP00000462852 ENST00000581714	Q7L1S5 [Direct mapping] Carbohydrate sulfotransferase 9 A0A024RC28 [Target identity:100%; Query identity:100%] Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9, isoform CRA_b Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0001537 [N-acetylgalactosamine 4-O-sulfotransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008146 [sulfotransferase activity] GO:0016021 [integral component of membrane] GO:0016051 [carbohydrate biosynthetic process] GO:0030166 [proteoglycan biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0030204 [chondroitin sulfate metabolic process] GO:0030206 [chondroitin sulfate biosynthetic process] GO:0042446 [hormone biosynthetic process] GO:0044281 [small molecule metabolic process] Show all	443 aa 52.1 kDa	No	0
CHST9-003 ENSP00000464655 ENST00000580774	Q7L1S5 [Direct mapping] Carbohydrate sulfotransferase 9 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0000139 [Golgi membrane] GO:0001537 [N-acetylgalactosamine 4-O-sulfotransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0016021 [integral component of membrane] GO:0016051 [carbohydrate biosynthetic process] GO:0030166 [proteoglycan biosynthetic process] GO:0030203 [glycosaminoglycan metabolic process] GO:0030204 [chondroitin sulfate metabolic process] GO:0030206 [chondroitin sulfate biosynthetic process] GO:0042446 [hormone biosynthetic process] GO:0044281 [small molecule metabolic process] Show all	74 aa 8.6 kDa	No	1
CHST9-201 ENSP00000284224 ENST00000284224	A0A0A0MQX9 [Direct mapping] Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9, isoform CRA_a; Carbohydrate sulfotransferase 9 Show all	Predicted intracellular proteins Show all	GO:0008146 [sulfotransferase activity] GO:0016021 [integral component of membrane] GO:0016051 [carbohydrate biosynthetic process] Show all	358 aa 42.1 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.