Tissue expression of PPP1R3A - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PPP1R3A
Gene description	Protein phosphatase 1, regulatory subunit 3A
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (heart muscle, skeletal muscle)
GTEx:	Group enriched (heart muscle, skeletal muscle)
FANTOM5:	Group enriched (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (heart muscle, skeletal muscle)

GENE INFORMATION
Gene name	PPP1R3A (HGNC Symbol)
Synonyms	GM, PPP1R3
Description	Protein phosphatase 1, regulatory subunit 3A (HGNC Symbol)
Entrez gene summary	The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	113876777 - 114075920
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154415 (version 83.38)
Entrez gene	5506
UniProt	Q16821 (UniProt - Evidence at protein level)
neXtProt	NX_Q16821
Antibodypedia	PPP1R3A antibodies

PROTEIN BROWSER

PPP1R3A-001	PPP1R3A-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPP1R3A-001 ENSP00000284601 ENST00000284601	Q16821 [Direct mapping] Protein phosphatase 1 regulatory subunit 3A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005977 [glycogen metabolic process] GO:0016021 [integral component of membrane] Show all	1122 aa 125.8 kDa	No	1
PPP1R3A-002 ENSP00000401278 ENST00000449795	C9JZB3 [Direct mapping] Protein phosphatase 1 regulatory subunit 3A Show all	Predicted intracellular proteins Show all		191 aa 20.9 kDa	No	0