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Most malignancies showed moderate cytoplasmic and/or membranous positivity. A few cases of squamous cell carcinomas in skin, lung and cervical cancers were strongly stained.
Q96PP8 [Direct mapping] Guanylate-binding protein 5
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MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0006954 [inflammatory response] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0031410 [cytoplasmic vesicle] GO:0042802 [identical protein binding] GO:0045089 [positive regulation of innate immune response] GO:0050702 [interleukin-1 beta secretion] GO:0051289 [protein homotetramerization] GO:0071346 [cellular response to interferon-gamma] GO:0072616 [interleukin-18 secretion] GO:1900017 [positive regulation of cytokine production involved in inflammatory response] GO:1900227 [positive regulation of NLRP3 inflammasome complex assembly]