Expression of GPR26 in cancer - Summary - The Human Protein Atlas

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GPR26

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPR26
Gene description	G protein-coupled receptor 26
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (breast cancer)
HPA (cell line):	Cell line enriched (SCLC-21H)
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct cytoplasmic expression in a subset of glial cell in cerebral cortex.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 1 antibody. HPA062736
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (breast cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA062736

GENE INFORMATION
Gene name	GPR26
Synonyms
Description	G protein-coupled receptor 26 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q26.13
Chromosome location (bp)	123666355 - 123694607
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154478 (version 83.38)
Entrez gene	2849
UniProt	Q8NDV2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NDV2
Antibodypedia	GPR26 antibodies

PROTEIN BROWSER

GPR26-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR26-001 ENSP00000284674 ENST00000284674	Q8NDV2 [Direct mapping] G-protein coupled receptor 26 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0031647 [regulation of protein stability] GO:1903955 [positive regulation of protein targeting to mitochondrion] Show all	337 aa 37.6 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.