Expression of MAGED4 in cancer - Summary - The Human Protein Atlas

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MAGED4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MAGED4
Gene description	Melanoma antigen family D4
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (A549, ASC TERT1, Hep G2)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA003554
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA003554

GENE INFORMATION
Gene name	MAGED4 (HGNC Symbol)
Synonyms	KIAA1859, MAGE-E1, MAGE1, MGC3210
Description	Melanoma antigen family D4 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	52184823 - 52192268
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154545 (version 83.38)
Entrez gene	728239
UniProt	Q96JG8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96JG8
Antibodypedia	MAGED4 antibodies

PROTEIN BROWSER

MAGED4-001	MAGED4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAGED4-001 ENSP00000364777 ENST00000375626	Q96JG8 [Direct mapping] Melanoma-associated antigen D4 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all		739 aa 81.1 kDa	No	0
MAGED4-201 ENSP00000472118 ENST00000599522	Q96JG8 [Direct mapping] Melanoma-associated antigen D4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		757 aa 83.2 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.