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BTG3

GENERAL INFORMATION

Gene name

 BTG3

Gene description

 BTG family, member 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues, including ciliated cells in fallopian tube.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA018400
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 BTG3 (HGNC Symbol)

Synonyms

 ANA, tob55

Description

 BTG family, member 3 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

 21

Cytoband

 q21.1

Chromosome location (bp)

 17593653 - 17612947

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154640 (version 83.38)

Entrez gene

 10950

UniProt

 Q14201 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14201

Antibodypedia

 BTG3 antibodies

PROTEIN BROWSER
BTG3-001
BTG3-002
BTG3-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BTG3-001
ENSP00000344609
ENST00000339775
Q14201 [Direct mapping]
Protein BTG3
Show all
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008285 [negative regulation of cell proliferation]
GO:0045930 [negative regulation of mitotic cell cycle]
Show all
 296 aa
34.2 kDa 		No 0
BTG3-002
ENSP00000284879
ENST00000348354
Q14201 [Direct mapping]
Protein BTG3
Q6IAU3 [Target identity:100%; Query identity:100%]
BTG family, member 3, isoform CRA_b; BTG3 protein; cDNA FLJ75072, highly similar to Homo sapiens BTG family, member 3 (BTG3), mRNA
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008285 [negative regulation of cell proliferation]
GO:0045930 [negative regulation of mitotic cell cycle]
Show all
 252 aa
29.1 kDa 		No 0
BTG3-003
ENSP00000413799
ENST00000457956
C9JLA2 [Direct mapping]
Protein BTG3
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 46 aa
5.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.