Expression of ANKRD40 in cancer - Summary - The Human Protein Atlas

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ANKRD40

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD40
Gene description	Ankyrin repeat domain 40
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA021668 , HPA021759
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA021668	HPA021759

GENE INFORMATION
Gene name	ANKRD40 (HGNC Symbol)
Synonyms	MGC15396
Description	Ankyrin repeat domain 40 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.33
Chromosome location (bp)	50693190 - 50707924
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154945 (version 83.38)
Entrez gene	91369
UniProt	Q6AI12 (UniProt - Evidence at protein level)
neXtProt	NX_Q6AI12
Antibodypedia	ANKRD40 antibodies

PROTEIN BROWSER

ANKRD40-001	ANKRD40-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD40-001 ENSP00000285243 ENST00000285243	Q6AI12 [Direct mapping] Ankyrin repeat domain-containing protein 40 A8IK34 [Target identity:100%; Query identity:100%] Ankyrin repeat domain 40; cDNA, FLJ94665 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	368 aa 41.1 kDa	No	0
ANKRD40-003 ENSP00000468442 ENST00000513072	K7ERW4 [Direct mapping] Ankyrin repeat domain-containing protein 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		122 aa 13.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.