Cell atlas - CNTNAP5 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CNTNAP5

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli fibrillar center
	Nucleus
	Vesicles

Human cell
	Nucleoli
	Nucleoplasm
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	CNTNAP5
Gene description	Contactin associated protein-like 5
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus & vesicles.
RNA cell category	Cell line enhanced (SH-SY5Y, AF22)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli fibrillar center (supported)
Additional location	In addition localized to the Nucleus (approved), Vesicles (approved)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA069095 , HPA069356
	SHOW MORE

ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, AF22) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli (fibrillar center). In addition localized to the nucleus & vesicles.

Main location

Nucleoli fibrillar center (supported)

Additional location

Nucleus (approved), Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA069095	CACO-2	Nucleoli fibrillar center
HPA069095	CACO-2	Vesicles
HPA069095	SH-SY5Y	Nucleus
		Nucleoli fibrillar center
		Vesicles
HPA069095	U-2 OS	Nucleus
		Nucleoli fibrillar center
		Vesicles
HPA069356	CACO-2	Nucleoli fibrillar center
HPA069356	SH-SY5Y	Nucleoli fibrillar center
HPA069356	U-2 OS	Nucleoli fibrillar center

GENE INFORMATION
Gene name	CNTNAP5 (HGNC Symbol)
Synonyms	caspr5, FLJ31966
Description	Contactin associated protein-like 5 (HGNC Symbol)
Entrez gene summary	This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q14.3
Chromosome location (bp)	124025287 - 124915287
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155052 (version 83.38)
Entrez gene	129684
UniProt	Q8WYK1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8WYK1
Antibodypedia	CNTNAP5 antibodies

PROTEIN BROWSER

CNTNAP5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CNTNAP5-001 ENSP00000399013 ENST00000431078	Q8WYK1 [Direct mapping] Contactin-associated protein-like 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0007155 [cell adhesion] GO:0016021 [integral component of membrane] Show all	1306 aa 145.6 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.