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LRGUK

GENERAL INFORMATION

Gene name

 LRGUK

Gene description

 Leucine-rich repeats and guanylate kinase domain containing

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (NTERA-2, SH-SY5Y, SK-MEL-30)
HPA (normal tissue):Group enriched (epididymis, fallopian tube, testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA029505 , HPA029506
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA029505
HPA029506

GENE INFORMATION

Gene name

 LRGUK (HGNC Symbol)

Synonyms

 CFAP246, FLJ32786

Description

 Leucine-rich repeats and guanylate kinase domain containing (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 q33

Chromosome location (bp)

 134127299 - 134264591

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000155530 (version 83.38)

Entrez gene

 136332

UniProt

 Q96M69 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96M69

Antibodypedia

 LRGUK antibodies

PROTEIN BROWSER
LRGUK-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LRGUK-001
ENSP00000285928
ENST00000285928
Q96M69 [Direct mapping]
Leucine-rich repeat and guanylate kinase domain-containing protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0001669 [acrosomal vesicle]
GO:0002177 [manchette]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007283 [spermatogenesis]
GO:0016301 [kinase activity]
GO:0016310 [phosphorylation]
GO:0035082 [axoneme assembly]
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 825 aa
93.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.