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ZKSCAN2

GENERAL INFORMATION

Gene name

 ZKSCAN2

Gene description

 Zinc finger with KRAB and SCAN domains 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA049141
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA049141

GENE INFORMATION

Gene name

 ZKSCAN2 (HGNC Symbol)

Synonyms

 FLJ23199, ZNF694, ZSCAN34

Description

 Zinc finger with KRAB and SCAN domains 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 16

Cytoband

 p12.1

Chromosome location (bp)

 25236001 - 25257931

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000155592 (version 83.38)

Entrez gene

 342357

UniProt

 Q63HK3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q63HK3

Antibodypedia

 ZKSCAN2 antibodies

PROTEIN BROWSER
ZKSCAN2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZKSCAN2-001
ENSP00000331626
ENST00000328086
Q63HK3 [Direct mapping]
Zinc finger protein with KRAB and SCAN domains 2
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003674 [molecular_function]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005575 [cellular_component]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0008150 [biological_process]
GO:0046872 [metal ion binding]
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 967 aa
110.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.