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LSM11

GENERAL INFORMATION

Gene name

 LSM11

Gene description

 LSM11, U7 small nuclear RNA associated

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA039587
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA039587

GENE INFORMATION

Gene name

 LSM11 (HGNC Symbol)

Synonyms

 FLJ38273

Description

 LSM11, U7 small nuclear RNA associated (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q33.3

Chromosome location (bp)

 157743695 - 157760709

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000155858 (version 83.38)

Entrez gene

 134353

UniProt

 P83369 (UniProt - Evidence at protein level)

neXtProt

 NX_P83369

Antibodypedia

 LSM11 antibodies

PROTEIN BROWSER
LSM11-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LSM11-001
ENSP00000286307
ENST00000286307
P83369 [Direct mapping]
U7 snRNA-associated Sm-like protein LSm11
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005683 [U7 snRNP]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006369 [termination of RNA polymerase II transcription]
GO:0006398 [histone mRNA 3'-end processing]
GO:0008334 [histone mRNA metabolic process]
GO:0010467 [gene expression]
GO:0031124 [mRNA 3'-end processing]
GO:0071204 [histone pre-mRNA 3'end processing complex]
GO:0071209 [U7 snRNA binding]
GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle]
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 360 aa
39.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.