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Cancer tissues showed weak to moderate cytoplasmic and membranous staining. Rare cases of prostate cancers and a single case of head and neck cancer and stomach cancer displayed strong positivity. Renal and liver cancers were negative.
GENE INFORMATION
Gene name
GNA14
Synonyms
Description
Guanine nucleotide binding protein (G protein), alpha 14 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]