Expression of RWDD2B in cancer - Summary - The Human Protein Atlas

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RWDD2B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RWDD2B
Gene description	RWD domain containing 2B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA018316
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA018316

GENE INFORMATION
Gene name	RWDD2B (HGNC Symbol)
Synonyms	C21orf6, GL011
Description	RWD domain containing 2B (HGNC Symbol)
Entrez gene summary
Chromosome	21
Cytoband	q21.3
Chromosome location (bp)	29004384 - 29019378
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156253 (version 83.38)
Entrez gene	10069
UniProt	P57060 (UniProt - Evidence at protein level)
neXtProt	NX_P57060
Antibodypedia	RWDD2B antibodies

PROTEIN BROWSER

RWDD2B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RWDD2B-001 ENSP00000418693 ENST00000493196	P57060 [Direct mapping] RWD domain-containing protein 2B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	319 aa 36.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.