Cell atlas - C14orf2 - The Human Protein Atlas

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C14orf2

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TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria
	Nucleoli fibrillar center

Human cell
	Mitochondria
	Nucleoli

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GENERAL INFORMATION
Gene name	C14orf2
Gene description	Chromosome 14 open reading frame 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria. In addition localized to the nucleoli (fibrillar center).
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (supported)
Additional location	In addition localized to the Nucleoli fibrillar center (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA058978
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria. In addition localized to the nucleoli (fibrillar center).

Main location

Mitochondria (supported)

Additional location

Nucleoli fibrillar center (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA058978	MCF7	Mitochondria
	HPA058978	PC-3	Nucleoli fibrillar center
	HPA058978	PC-3	Mitochondria
	HPA058978	U-2 OS	Nucleoli fibrillar center
	HPA058978	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	C14orf2 (HGNC Symbol)
Synonyms	MP68
Description	Chromosome 14 open reading frame 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.33
Chromosome location (bp)	103912288 - 103928269
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156411 (version 83.38)
Entrez gene	9556
UniProt	P56378 (UniProt - Evidence at protein level)
neXtProt	NX_P56378
Antibodypedia	C14orf2 antibodies

PROTEIN BROWSER

C14orf2-001	C14orf2-002	C14orf2-004	C14orf2-005	C14orf2-007	C14orf2-010	C14orf2-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C14orf2-001 ENSP00000286953 ENST00000286953	P56378 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	58 aa 6.7 kDa	No	0
C14orf2-002 ENSP00000452462 ENST00000553430	A0A0A0MTQ5 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0016021 [integral component of membrane] Show all	77 aa 9.1 kDa	No	0
C14orf2-004 ENSP00000451500 ENST00000554713	G3V556 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	99 aa 11.3 kDa	No	1
C14orf2-005 ENSP00000401770 ENST00000414262	P56378 [Direct mapping] 6.8 kDa mitochondrial proteolipid A0A024R6N3 [Target identity:100%; Query identity:100%] Chromosome 14 open reading frame 2, isoform CRA_c Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	75 aa 8.6 kDa	No	0
C14orf2-007 ENSP00000452133 ENST00000554880	P56378 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	58 aa 6.7 kDa	No	0
C14orf2-010 ENSP00000452186 ENST00000555030	G3V556 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	99 aa 11.3 kDa	No	1
C14orf2-012 ENSP00000450894 ENST00000557040	P56378 [Direct mapping] 6.8 kDa mitochondrial proteolipid Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0005739 [mitochondrion] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	58 aa 6.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.