Fields »
ABOUT
HELP
BLOG
SH3RF2

GENERAL INFORMATION

Gene name

 SH3RF2

Gene description

 SH3 domain containing ring finger 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (CACO-2)
HPA (normal tissue):Tissue enhanced (skin)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA058119
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Stomach cancer

STAINING SUMMARY
HPA058119

GENE INFORMATION

Gene name

 SH3RF2 (HGNC Symbol)

Synonyms

 FLJ23654, Hepp1, POSHER, PPP1R39, RNF158

Description

 SH3 domain containing ring finger 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 145936579 - 146081791

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000156463 (version 83.38)

Entrez gene

 153769

UniProt

 Q8TEC5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TEC5

Antibodypedia

 SH3RF2 antibodies

PROTEIN BROWSER
SH3RF2-001
SH3RF2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SH3RF2-001
ENSP00000352028
ENST00000359120
Q8TEC5 [Direct mapping]
Putative E3 ubiquitin-protein ligase SH3RF2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004864 [protein phosphatase inhibitor activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0008157 [protein phosphatase 1 binding]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0019902 [phosphatase binding]
GO:0046872 [metal ion binding]
Show all
 729 aa
79.3 kDa 		No 0
SH3RF2-002
ENSP00000424497
ENST00000511217
Q8TEC5 [Direct mapping]
Putative E3 ubiquitin-protein ligase SH3RF2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004864 [protein phosphatase inhibitor activity]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0008157 [protein phosphatase 1 binding]
GO:0008270 [zinc ion binding]
GO:0010923 [negative regulation of phosphatase activity]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0019902 [phosphatase binding]
GO:0046872 [metal ion binding]
Show all
 729 aa
79.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.