Cell atlas - FRRS1 - The Human Protein Atlas

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FRRS1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	FRRS1
Gene description	Ferric-chelate reductase 1
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (HEL)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HEL) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	FRRS1 (HGNC Symbol)
Synonyms	SDFR2, SDR2
Description	Ferric-chelate reductase 1 (HGNC Symbol)
Entrez gene summary	Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p21.2
Chromosome location (bp)	99708703 - 99766631
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156869 (version 83.38)
Entrez gene	391059
UniProt	Q6ZNA5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZNA5
Antibodypedia	FRRS1 antibodies

PROTEIN BROWSER

FRRS1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FRRS1-001 ENSP00000287474 ENST00000287474	Q6ZNA5 [Direct mapping] Ferric-chelate reductase 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000293 [ferric-chelate reductase activity] GO:0016021 [integral component of membrane] GO:0046872 [metal ion binding] GO:0055114 [oxidation-reduction process] Show all	626 aa 70.5 kDa	Yes	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.