Expression of SHCBP1L in cancer - Summary - The Human Protein Atlas

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SHCBP1L

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SHCBP1L
Gene description	SHC SH2-domain binding protein 1-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (cervical cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective cytoplasmic expression in a subset of cells in seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 3 antibodies. HPA036124 , HPA036125 , HPA064821
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (cervical cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036124	HPA036125	HPA064821

GENE INFORMATION
Gene name	SHCBP1L (HGNC Symbol)
Synonyms	C1orf14
Description	SHC SH2-domain binding protein 1-like (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q25.3
Chromosome location (bp)	182899865 - 182953525
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157060 (version 83.38)
Entrez gene	81626
UniProt	Q9BZQ2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BZQ2
Antibodypedia	SHCBP1L antibodies

PROTEIN BROWSER

SHCBP1L-001	SHCBP1L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SHCBP1L-001 ENSP00000356518 ENST00000367547	Q9BZQ2 [Direct mapping] SHC SH2 domain-binding protein 1-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	653 aa 72.6 kDa	No	0
SHCBP1L-201 ENSP00000397308 ENST00000423786	A0A0A0MSN2 [Direct mapping] SHC SH2 domain-binding protein 1-like protein Show all	Predicted intracellular proteins Show all		724 aa 80.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.