Expression of CIB4 in cancer - Summary - The Human Protein Atlas

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CIB4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CIB4
Gene description	Calcium and integrin binding family member 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (thyroid cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (testis, thyroid gland)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA036130 , HPA036131
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (thyroid cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036130	HPA036131

GENE INFORMATION
Gene name	CIB4
Synonyms
Description	Calcium and integrin binding family member 4 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	26581202 - 26641368
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000157884 (version 83.38)
Entrez gene	130106
UniProt	A0PJX0 (UniProt - Evidence at protein level)
neXtProt	NX_A0PJX0
Antibodypedia	CIB4 antibodies

PROTEIN BROWSER

CIB4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CIB4-001 ENSP00000288861 ENST00000288861	A0PJX0 [Direct mapping] Calcium and integrin-binding family member 4 Show all	Predicted intracellular proteins Show all	GO:0000287 [magnesium ion binding] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	185 aa 21.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.