Expression of LRRC43 in cancer - Summary - The Human Protein Atlas

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LRRC43

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LRRC43
Gene description	Leucine rich repeat containing 43
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HUVEC TERT2, SCLC-21H)
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA047606
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047606

GENE INFORMATION
Gene name	LRRC43 (HGNC Symbol)
Synonyms	MGC35140
Description	Leucine rich repeat containing 43 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.31
Chromosome location (bp)	122167738 - 122203471
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000158113 (version 83.38)
Entrez gene	254050
UniProt	Q8N309 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N309
Antibodypedia	LRRC43 antibodies

PROTEIN BROWSER

LRRC43-001	LRRC43-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC43-001 ENSP00000344233 ENST00000339777	Q8N309 [Direct mapping] Leucine-rich repeat-containing protein 43 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	656 aa 73 kDa	No	0
LRRC43-006 ENSP00000438751 ENST00000537729	F5H0N3 [Direct mapping] Leucine-rich repeat-containing protein 43 Show all	Predicted intracellular proteins Show all		147 aa 16.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.