Expression of AAED1 in cancer - Summary - The Human Protein Atlas

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AAED1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AAED1
Gene description	AhpC/TSA antioxidant enzyme domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA021294
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA021294

GENE INFORMATION
Gene name	AAED1 (HGNC Symbol)
Synonyms	C9orf21
Description	AhpC/TSA antioxidant enzyme domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q22.33
Chromosome location (bp)	96639577 - 96655303
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158122 (version 83.38)
Entrez gene	195827
UniProt	Q7RTV5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7RTV5
Antibodypedia	AAED1 antibodies

PROTEIN BROWSER

AAED1-001	AAED1-002	AAED1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AAED1-001 ENSP00000398933 ENST00000446045	H0Y5J5 [Direct mapping] Thioredoxin-like protein AAED1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		180 aa 20.1 kDa	No	0
AAED1-002 ENSP00000364382 ENST00000375234	Q7RTV5 [Direct mapping] Thioredoxin-like protein AAED1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		226 aa 24.9 kDa	No	0
AAED1-003 ENSP00000412378 ENST00000411939	H0Y7F1 [Direct mapping] Thioredoxin-like protein AAED1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 12.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.