Cell atlas - CD1B - The Human Protein Atlas

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CD1B

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CD1B
Gene description	CD1b molecule
Protein class	CD markers Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (MOLT-4)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (MOLT-4) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CD1B (HGNC Symbol)
Synonyms	CD1
Description	CD1b molecule (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q23.1
Chromosome location (bp)	158327951 - 158331531
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158485 (version 83.38)
Entrez gene	910
UniProt	P29016 (UniProt - Evidence at protein level)
neXtProt	NX_P29016
Antibodypedia	CD1B antibodies

PROTEIN BROWSER

CD1B-001	CD1B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD1B-001 ENSP00000357150 ENST00000368168	P29016 [Direct mapping] T-cell surface glycoprotein CD1b Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0002250 [adaptive immune response] GO:0005515 [protein binding] GO:0005765 [lysosomal membrane] GO:0005886 [plasma membrane] GO:0009986 [cell surface] GO:0010008 [endosome membrane] GO:0016021 [integral component of membrane] GO:0030881 [beta-2-microglobulin binding] GO:0030883 [endogenous lipid antigen binding] GO:0030884 [exogenous lipid antigen binding] GO:0048007 [antigen processing and presentation, exogenous lipid antigen via MHC class Ib] GO:0071723 [lipopeptide binding] Show all	333 aa 36.9 kDa	Yes	1
CD1B-002 ENSP00000395161 ENST00000451207	H7C0I2 [Direct mapping] T-cell surface glycoprotein CD1b Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0006955 [immune response] GO:0016021 [integral component of membrane] Show all	246 aa 27.1 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.