Expression of PAGE5 in cancer - Summary - The Human Protein Atlas

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PAGE5

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PAGE5
Gene description	P antigen family, member 5 (prostate associated)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (liver cancer, melanoma, testis cancer)
HPA (cell line):	Group enriched (Karpas-707, U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in cells of seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Supported based on 1 antibody. HPA052619
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (liver cancer, melanoma, testis cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052619

GENE INFORMATION
Gene name	PAGE5 (HGNC Symbol)
Synonyms	CT16.1, CT16.2, PAGE-5
Description	P antigen family, member 5 (prostate associated) (HGNC Symbol)
Entrez gene summary	This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015]
Chromosome	X
Cytoband	p11.21
Chromosome location (bp)	55220355 - 55224108
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000158639 (version 83.38)
Entrez gene	90737
UniProt	Q96GU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96GU1
Antibodypedia	PAGE5 antibodies

PROTEIN BROWSER

PAGE5-001	PAGE5-002	PAGE5-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PAGE5-001 ENSP00000289619 ENST00000289619	Q96GU1 [Direct mapping] P antigen family member 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		130 aa 14 kDa	No	0
PAGE5-002 ENSP00000364093 ENST00000374955	Q96GU1 [Direct mapping] P antigen family member 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		110 aa 11.8 kDa	No	0
PAGE5-003 ENSP00000364090 ENST00000374952	Q5JUL1 [Direct mapping] P antigen family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		93 aa 10.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.