Expression of PTMS in cancer - Summary - The Human Protein Atlas

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PTMS

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PTMS
Gene description	Parathymosin
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. External characterization data supports antibody staining. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA038186
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038186

GENE INFORMATION
Gene name	PTMS (HGNC Symbol)
Synonyms	ParaT
Description	Parathymosin (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	6765516 - 6770952
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159335 (version 83.38)
Entrez gene	5763
UniProt	P20962 (UniProt - Evidence at protein level)
neXtProt	NX_P20962
Antibodypedia	PTMS antibodies

PROTEIN BROWSER

PTMS-001	PTMS-005	PTMS-006	PTMS-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PTMS-001 ENSP00000310088 ENST00000309083	P20962 [Direct mapping] Parathymosin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002376 [immune system process] GO:0005634 [nucleus] GO:0006260 [DNA replication] Show all	102 aa 11.5 kDa	No	0
PTMS-005 ENSP00000374113 ENST00000389462	F5GXR3 [Direct mapping] Parathymosin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		104 aa 12.1 kDa	No	0
PTMS-006 ENSP00000442325 ENST00000540874	F5H7R9 [Direct mapping] Parathymosin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.3 kDa	No	0
PTMS-201 ENSP00000478828 ENST00000619580	P20962 [Direct mapping] Parathymosin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002376 [immune system process] GO:0005634 [nucleus] GO:0006260 [DNA replication] Show all	102 aa 11.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.