Cell atlas - ADIPOR1 - The Human Protein Atlas

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ADIPOR1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ADIPOR1
Gene description	Adiponectin receptor 1
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ADIPOR1 (HGNC Symbol)
Synonyms	ACDCR1, PAQR1
Description	Adiponectin receptor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
Chromosome	1
Cytoband	q32.1
Chromosome location (bp)	202940823 - 202958572
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159346 (version 83.38)
Entrez gene	51094
UniProt	Q96A54 (UniProt - Evidence at protein level)
neXtProt	NX_Q96A54
Antibodypedia	ADIPOR1 antibodies

PROTEIN BROWSER

ADIPOR1-001	ADIPOR1-002	ADIPOR1-003	ADIPOR1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADIPOR1-001 ENSP00000341785 ENST00000340990	Q96A54 [Direct mapping] Adiponectin receptor protein 1 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0009755 [hormone-mediated signaling pathway] GO:0010906 [regulation of glucose metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019216 [regulation of lipid metabolic process] GO:0019395 [fatty acid oxidation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0031226 [intrinsic component of plasma membrane] GO:0033210 [leptin-mediated signaling pathway] GO:0033211 [adiponectin-activated signaling pathway] GO:0042593 [glucose homeostasis] GO:0042802 [identical protein binding] GO:0046427 [positive regulation of JAK-STAT cascade] GO:0046628 [positive regulation of insulin receptor signaling pathway] GO:0046872 [metal ion binding] GO:0046982 [protein heterodimerization activity] GO:0055100 [adiponectin binding] GO:0097003 [adipokinetic hormone receptor activity] Show all	375 aa 42.6 kDa	No	7
ADIPOR1-002 ENSP00000402178 ENST00000417068	C9JNM5 [Direct mapping] Adiponectin receptor protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	266 aa 30.6 kDa	No	4
ADIPOR1-003 ENSP00000392946 ENST00000426229	C9J0W7 [Direct mapping] Adiponectin receptor protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	205 aa 23.6 kDa	No	2
ADIPOR1-201 ENSP00000356223 ENST00000367254	F8W782 [Direct mapping] Adiponectin receptor protein 1 Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004872 [receptor activity] GO:0016021 [integral component of membrane] GO:0033211 [adiponectin-activated signaling pathway] Show all	171 aa 19.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.