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RNA cell line category: Cell line enhanced (U-87 MG)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
HK2
Synonyms
Description
Hexokinase 2 (HGNC Symbol)
Entrez gene summary
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001678 [cellular glucose homeostasis] GO:0002931 [response to ischemia] GO:0004340 [glucokinase activity] GO:0004396 [hexokinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005536 [glucose binding] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0006006 [glucose metabolic process] GO:0006096 [glycolytic process] GO:0007595 [lactation] GO:0008637 [apoptotic mitochondrial changes] GO:0008645 [hexose transport] GO:0008865 [fructokinase activity] GO:0015758 [glucose transport] GO:0016020 [membrane] GO:0016773 [phosphotransferase activity, alcohol group as acceptor] GO:0019158 [mannokinase activity] GO:0035795 [negative regulation of mitochondrial membrane permeability] GO:0044281 [small molecule metabolic process] GO:0046324 [regulation of glucose import] GO:0046835 [carbohydrate phosphorylation] GO:0051156 [glucose 6-phosphate metabolic process] GO:0055085 [transmembrane transport] GO:0061621 [canonical glycolysis] GO:0072655 [establishment of protein localization to mitochondrion] GO:0072656 [maintenance of protein location in mitochondrion] GO:1903599 [positive regulation of mitophagy] GO:2000378 [negative regulation of reactive oxygen species metabolic process]
