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A majority of cancers displayed weak to moderate cytoplasmic positivity. Additional membranous positivity was observed in colorectal cancers while a few cases of melanomas showed additional nuclear positivity. Several cases of gliomas, lymphomas, squamous and basal cell carcinomas were negative.
GENE INFORMATION
Gene name
RSPRY1 (HGNC Symbol)
Synonyms
KIAA1972
Description
Ring finger and SPRY domain containing 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a glycoprotein that contains a RING-type zinc finger domain and an SPRY domain of unknown function. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Q96DX4 [Direct mapping] RING finger and SPRY domain-containing protein 1 A0A024R6U0 [Target identity:100%; Query identity:100%] Ring finger and SPRY domain containing 1, isoform CRA_a
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Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q96DX4 [Direct mapping] RING finger and SPRY domain-containing protein 1 A0A024R6U0 [Target identity:100%; Query identity:100%] Ring finger and SPRY domain containing 1, isoform CRA_a
Show all
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Ezkurdia et al 2014)