Expression of CCDC17 in cancer - Summary

GENERAL INFORMATION
Gene name	CCDC17
Gene description	Coiled-coil domain containing 17
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in ciliated cells of fallopian tube and respiratory epithelia.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA028338
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

STAINING SUMMARY

HPA028338

GENE INFORMATION
Gene name	CCDC17 (HGNC Symbol)
Synonyms	FLJ33084
Description	Coiled-coil domain containing 17 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p34.1
Chromosome location (bp)	45620044 - 45624057
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159588 (version 83.38)
Entrez gene	149483
UniProt	Q96LX7 (UniProt - Evidence at protein level)
neXtProt	NX_Q96LX7
Antibodypedia	CCDC17 antibodies

PROTEIN BROWSER

CCDC17-008	CCDC17-009	CCDC17-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC17-008 ENSP00000432172 ENST00000528266	Q96LX7 [Direct mapping] Coiled-coil domain-containing protein 17 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	622 aa 67.7 kDa	No	0
CCDC17-009 ENSP00000389415 ENST00000421127	Q96LX7 [Direct mapping] Coiled-coil domain-containing protein 17 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	613 aa 66.6 kDa	No	0
CCDC17-010 ENSP00000411335 ENST00000445048	Q96LX7 [Direct mapping] Coiled-coil domain-containing protein 17 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	110 aa 11.6 kDa	No	0