Tissue expression of AGPAT3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	AGPAT3
Gene description	1-acylglycerol-3-phosphate O-acyltransferase 3
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	AGPAT3 (HGNC Symbol)
Synonyms	LPAAT-gamma
Description	1-acylglycerol-3-phosphate O-acyltransferase 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	21
Cytoband	q22.3
Chromosome location (bp)	43865186 - 43986536
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160216 (version 83.38)
Entrez gene	56894
UniProt	Q9NRZ7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NRZ7
Antibodypedia	AGPAT3 antibodies

PROTEIN BROWSER

AGPAT3-001	AGPAT3-002	AGPAT3-003	AGPAT3-004	AGPAT3-005	AGPAT3-008	AGPAT3-010	AGPAT3-011	AGPAT3-012	AGPAT3-014	AGPAT3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AGPAT3-001 ENSP00000291572 ENST00000291572	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4
AGPAT3-002 ENSP00000381138 ENST00000398061	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4
AGPAT3-003 ENSP00000332989 ENST00000327505	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4
AGPAT3-004 ENSP00000381140 ENST00000398063	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0042171 [lysophosphatidic acid acyltransferase activity] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4
AGPAT3-005 ENSP00000381135 ENST00000398058	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4
AGPAT3-008 ENSP00000389318 ENST00000448287	C9JQX8 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	79 aa 9.2 kDa	No	2
AGPAT3-010 ENSP00000412079 ENST00000445582	C9J184 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	128 aa 14.8 kDa	No	2
AGPAT3-011 ENSP00000413906 ENST00000457068	C9JL26 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016746 [transferase activity, transferring acyl groups] Show all	255 aa 29.6 kDa	No	2
AGPAT3-012 ENSP00000394102 ENST00000448845	C9JK35 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	38 aa 4.2 kDa	No	1
AGPAT3-014 ENSP00000414440 ENST00000422850	C9JL26 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016746 [transferase activity, transferring acyl groups] Show all	255 aa 29.6 kDa	No	2
AGPAT3-201 ENSP00000443510 ENST00000546158	Q9NRZ7 [Direct mapping] 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0008654 [phospholipid biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016024 [CDP-diacylglycerol biosynthetic process] GO:0016746 [transferase activity, transferring acyl groups] GO:0019432 [triglyceride biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] Show all	376 aa 43.4 kDa	No	4