Expression of GPATCH4 in cancer - Summary - The Human Protein Atlas

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GPATCH4

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPATCH4
Gene description	G patch domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA028323
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and renal cancer (unfavourable).
Liver cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028323

GENE INFORMATION
Gene name	GPATCH4 (HGNC Symbol)
Synonyms	DKFZP434F1735, FLJ20249, GPATC4
Description	G patch domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband
Chromosome location (bp)	156594487 - 156601496
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160818 (version 83.38)
Entrez gene	54865
UniProt
neXtProt
Antibodypedia	GPATCH4 antibodies

PROTEIN BROWSER

GPATCH4-001	GPATCH4-009	GPATCH4-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPATCH4-001 ENSP00000357215 ENST00000368232	A0A0A0MRK1 [Direct mapping] G patch domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	370 aa 42.1 kDa	No	0
GPATCH4-009 ENSP00000412620 ENST00000415314	F8W895 [Direct mapping] G patch domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	264 aa 29.5 kDa	No	0
GPATCH4-015 ENSP00000396441 ENST00000438976	E9PAV9 [Direct mapping] G patch domain-containing protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002244 [hematopoietic progenitor cell differentiation] GO:0003676 [nucleic acid binding] Show all	375 aa 42.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.