Expression of CCDC105 in cancer - Summary

GENERAL INFORMATION
Gene name	CCDC105
Gene description	Coiled-coil domain containing 105
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in several different cell types, including subsets of cells in seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA058585
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

STAINING SUMMARY

HPA058585

GENE INFORMATION
Gene name	CCDC105 (HGNC Symbol)
Synonyms	FLJ40365
Description	Coiled-coil domain containing 105 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.12
Chromosome location (bp)	15010744 - 15023269
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160994 (version 83.38)
Entrez gene	126402
UniProt	Q8IYK2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYK2
Antibodypedia	CCDC105 antibodies

PROTEIN BROWSER

CCDC105-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC105-001 ENSP00000292574 ENST00000292574	Q8IYK2 [Direct mapping] Coiled-coil domain-containing protein 105 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0070062 [extracellular exosome] Show all	499 aa 56.9 kDa	No	0