Expression of LRRC56 in cancer - Summary - The Human Protein Atlas

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LRRC56

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LRRC56
Gene description	Leucine rich repeat containing 56
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (AN3-CA, Karpas-707, T-47d)
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA038728
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PROGNOSTIC SUMMARY
Prognostic marker in lung cancer (favourable), pancreatic cancer (favourable) and endometrial cancer (favourable).
Lung cancer p<0.001 Pancreatic cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038728

GENE INFORMATION
Gene name	LRRC56 (HGNC Symbol)
Synonyms	DKFZp761L1518, FLJ00101
Description	Leucine rich repeat containing 56 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.5
Chromosome location (bp)	537527 - 554916
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000161328 (version 83.38)
Entrez gene	115399
UniProt	Q8IYG6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYG6
Antibodypedia	LRRC56 antibodies

PROTEIN BROWSER

LRRC56-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC56-001 ENSP00000270115 ENST00000270115	Q8IYG6 [Direct mapping] Leucine-rich repeat-containing protein 56 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	542 aa 58.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.