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SAP30BP

GENERAL INFORMATION

Gene name

 SAP30BP

Gene description

 SAP30 binding protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous nuclear and nuclear membrane expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA052943
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and renal cancer (unfavourable).
0.00.10.20.30.40.50.60.70.80.91.0 0 1 2 3 4 5 6 7 8 910 Liver cancer p<0.001
0.00.10.20.30.40.50.60.70.80.91.0 0 1 2 3 4 5 6 7 8 910111213141516 Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all
0.05.01015202530354045FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA052943

Cancer

Cancer staining

Protein
expression of
normal tissue
Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue
Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

 Cancer tissues showed moderate to strong nuclear / nuclear membranous staining.

GENE INFORMATION

Gene name

 SAP30BP (HGNC Symbol)

Synonyms

 HCNGP, HTRG, HTRP

Description

 SAP30 binding protein (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q25.1

Chromosome location (bp)

 75667116 - 75708062

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161526 (version 83.38)

Entrez gene

 29115

UniProt

 Q9UHR5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UHR5

Antibodypedia

 SAP30BP antibodies

PROTEIN BROWSER
SAP30BP-001
SAP30BP-002
SAP30BP-015
SAP30BP-017
SAP30BP-026
SAP30BP-027

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SAP30BP-001
ENSP00000462116
ENST00000584667
Q9UHR5 [Direct mapping]
SAP30-binding protein
A0A024R8R0 [Target identity:100%; Query identity:100%]
SAP30 binding protein, isoform CRA_a
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006915 [apoptotic process]
GO:0010467 [gene expression]
GO:0010942 [positive regulation of cell death]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045111 [intermediate filament cytoskeleton]
GO:0045814 [negative regulation of gene expression, epigenetic]
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 308 aa
33.9 kDa 		No 0
SAP30BP-002
ENSP00000347592
ENST00000355423
Q9UHR5 [Direct mapping]
SAP30-binding protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006915 [apoptotic process]
GO:0010467 [gene expression]
GO:0010942 [positive regulation of cell death]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045111 [intermediate filament cytoskeleton]
GO:0045814 [negative regulation of gene expression, epigenetic]
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 292 aa
32.1 kDa 		No 0
SAP30BP-015
ENSP00000463758
ENST00000583536
J3QQJ0 [Direct mapping]
SAP30-binding protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0006355 [regulation of transcription, DNA-templated]
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 325 aa
35.8 kDa 		No 0
SAP30BP-017
ENSP00000462255
ENST00000578909
J3KS14 [Direct mapping]
SAP30-binding protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0006355 [regulation of transcription, DNA-templated]
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 104 aa
11.6 kDa 		No 0
SAP30BP-026
ENSP00000463615
ENST00000584240
J3QLM2 [Direct mapping]
SAP30-binding protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
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 93 aa
11 kDa 		No 0
SAP30BP-027
ENSP00000462133
ENST00000583063
J3KRR6 [Direct mapping]
SAP30-binding protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
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 109 aa
13 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.