Cell atlas - PRPSAP1 - The Human Protein Atlas

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PRPSAP1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	PRPSAP1
Gene description	Phosphoribosyl pyrophosphate synthetase-associated protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA062396
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA062396	HEK 293	Cytosol
	HPA062396	Hep G2	Cytosol
	HPA062396	U-2 OS	Cytosol

GENE INFORMATION
Gene name	PRPSAP1 (HGNC Symbol)
Synonyms	PAP39
Description	Phosphoribosyl pyrophosphate synthetase-associated protein 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	76309486 - 76384521
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000161542 (version 83.38)
Entrez gene	5635
UniProt	Q14558 (UniProt - Evidence at protein level)
neXtProt	NX_Q14558
Antibodypedia	PRPSAP1 antibodies

PROTEIN BROWSER

PRPSAP1-001	PRPSAP1-002	PRPSAP1-003	PRPSAP1-004	PRPSAP1-005	PRPSAP1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRPSAP1-001 ENSP00000414624 ENST00000446526	Q14558 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0002189 [ribose phosphate diphosphokinase complex] GO:0004749 [ribose phosphate diphosphokinase activity] GO:0004857 [enzyme inhibitor activity] GO:0005515 [protein binding] GO:0006139 [nucleobase-containing compound metabolic process] GO:0009165 [nucleotide biosynthetic process] GO:0019900 [kinase binding] GO:0030234 [enzyme regulator activity] GO:0033673 [negative regulation of kinase activity] GO:0043234 [protein complex] Show all	385 aa 42.5 kDa	No	0
PRPSAP1-002 ENSP00000314973 ENST00000324684	B4DP31 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1; cDNA FLJ57408, highly similar to Phosphoribosyl pyrophosphatesynthetase-associated protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004749 [ribose phosphate diphosphokinase activity] GO:0009165 [nucleotide biosynthetic process] Show all	282 aa 31.3 kDa	No	0
PRPSAP1-003 ENSP00000392838 ENST00000435555	C9J168 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004749 [ribose phosphate diphosphokinase activity] GO:0009165 [nucleotide biosynthetic process] Show all	230 aa 25.4 kDa	No	0
PRPSAP1-004 ENSP00000409190 ENST00000423915	C9JKT9 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		89 aa 10.1 kDa	No	0
PRPSAP1-005 ENSP00000402126 ENST00000442767	C9JNQ3 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		104 aa 11.5 kDa	No	0
PRPSAP1-007 ENSP00000387494 ENST00000436498	C9JUN4 [Direct mapping] Phosphoribosyl pyrophosphate synthase-associated protein 1 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004749 [ribose phosphate diphosphokinase activity] GO:0009165 [nucleotide biosynthetic process] Show all	157 aa 17.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.