Tissue expression of KRT82 - Summary - The Human Protein Atlas

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KRT82

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	KRT82
Gene description	Keratin 82, type II
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Not detected
GTEx:	Tissue enriched (skin)

Protein evidence

Evidence at protein level

Protein expression

Highly expressed in hair cuticle.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. External characterization data supports antibody staining pattern while RNA data does not.
Reliability score	Supported based on 2 antibodies. HPA058715 , HPA067230
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Hair

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Not detected
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (skin)

GENE INFORMATION
Gene name	KRT82 (HGNC Symbol)
Synonyms	Hb-2, KRTHB2
Description	Keratin 82, type II (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	52393931 - 52406355
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000161850 (version 83.38)
Entrez gene	3888
UniProt	Q9NSB4 (UniProt - Inferred from homology)
neXtProt	NX_Q9NSB4
Antibodypedia	KRT82 antibodies

PROTEIN BROWSER

KRT82-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT82-001 ENSP00000257974 ENST00000257974	Q9NSB4 [Direct mapping] Keratin, type II cuticular Hb2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] GO:0008150 [biological_process] GO:0030280 [structural constituent of epidermis] GO:0045095 [keratin filament] Show all	513 aa 56.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.