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RPL26

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GENERAL INFORMATION

Gene name

 RPL26

Gene description

 Ribosomal protein L26

Protein class

 Disease related genes
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 9
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Endoplasmic reticulum (supported), Cytosol (supported)

Additional location

 In addition localized to the Nucleoli (approved)

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA030449
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

 Endoplasmic reticulum (supported), Cytosol (supported)

Additional location

 Nucleoli (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA030449 A-431 Nucleoli
Endoplasmic reticulum
Cytosol
HPA030449 U-2 OS Nucleoli
Endoplasmic reticulum
Cytosol
HPA030449 U-251 MG Endoplasmic reticulum
Cytosol

GENE INFORMATION

Gene name

 RPL26 (HGNC Symbol)

Synonyms

 L26

Description

 Ribosomal protein L26 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Chromosome

 17

Cytoband

 p13.1

Chromosome location (bp)

 8377520 - 8383213

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161970 (version 83.38)

Entrez gene

 6154

UniProt

 P61254 (UniProt - Evidence at protein level)

neXtProt

 NX_P61254

Antibodypedia

 RPL26 antibodies

PROTEIN BROWSER
RPL26-001
RPL26-003
RPL26-004
RPL26-005
RPL26-006
RPL26-007
RPL26-008
RPL26-012
RPL26-013

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL26-001
ENSP00000293842
ENST00000293842
P61254 [Direct mapping]
60S ribosomal protein L26
Show all
Ribosomal proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006364 [rRNA processing]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 145 aa
17.3 kDa 		No 0
RPL26-003
ENSP00000463910
ENST00000578812
J3QQV1 [Direct mapping]
60S ribosomal protein L26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 110 aa
12.9 kDa 		No 0
RPL26-004
ENSP00000463784
ENST00000584164
P61254 [Direct mapping]
60S ribosomal protein L26
Show all
Ribosomal proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006364 [rRNA processing]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 145 aa
17.3 kDa 		No 0
RPL26-005
ENSP00000463470
ENST00000582556
P61254 [Direct mapping]
60S ribosomal protein L26
Show all
Ribosomal proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006364 [rRNA processing]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 145 aa
17.3 kDa 		No 0
RPL26-006
ENSP00000463021
ENST00000583515
J3KTJ8 [Direct mapping]
60S ribosomal protein L26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 97 aa
11.6 kDa 		No 0
RPL26-007
ENSP00000462322
ENST00000583011
P61254 [Direct mapping]
60S ribosomal protein L26
Show all
Ribosomal proteins
Predicted intracellular proteins
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0002181 [cytoplasmic translation]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006364 [rRNA processing]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0015934 [large ribosomal subunit]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 145 aa
17.3 kDa 		No 0
RPL26-008
ENSP00000464239
ENST00000584343
J3QRI7 [Direct mapping]
60S ribosomal protein L26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 107 aa
12.6 kDa 		No 0
RPL26-012
ENSP00000462249
ENST00000584441
J3KS10 [Direct mapping]
60S ribosomal protein L26
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 63 aa
7.3 kDa 		No 0
RPL26-013
ENSP00000464143
ENST00000582485
J3QRC4 [Direct mapping]
60S ribosomal protein L26
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0015934 [large ribosomal subunit]
Show all
 135 aa
15.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.