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A majority of cancer tissues showed weak to moderate cytoplasmic positivity. Most papillary adenocarcinomas of thyroid showed strong immunoreactivity.
GENE INFORMATION
Gene name
ADCY9 (HGNC Symbol)
Synonyms
AC9
Description
Adenylate cyclase 9 (HGNC Symbol)
Entrez gene summary
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]