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GNG3

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GENERAL INFORMATION

Gene name

 GNG3

Gene description

 Guanine nucleotide binding protein (G protein), gamma 3

Protein class

 Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Group enriched (SCLC-21H, Karpas-707)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (SCLC-21H, Karpas-707)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 GNG3

Synonyms

Description

 Guanine nucleotide binding protein (G protein), gamma 3 (HGNC Symbol)

Entrez gene summary

 Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The gamma subunit determines the specificity of which signaling pathways will be affected by this particular complex. The protein encoded by this gene represents the gamma subunit of both inhibitory and stimulatory complexes. [provided by RefSeq, Jan 2012]

Chromosome

 11

Cytoband

 q12.3

Chromosome location (bp)

 62707658 - 62709201

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162188 (version 83.38)

Entrez gene

 2785

UniProt

 P63215 (UniProt - Inferred from homology)

neXtProt

 NX_P63215

Antibodypedia

 GNG3 antibodies

PROTEIN BROWSER
GNG3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GNG3-001
ENSP00000294117
ENST00000294117
P63215 [Direct mapping]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000187 [activation of MAPK activity]
GO:0001664 [G-protein coupled receptor binding]
GO:0003924 [GTPase activity]
GO:0004871 [signal transducer activity]
GO:0005829 [cytosol]
GO:0005834 [heterotrimeric G-protein complex]
GO:0005886 [plasma membrane]
GO:0006112 [energy reserve metabolic process]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007268 [synaptic transmission]
GO:0031702 [type 1 angiotensin receptor binding]
GO:0044281 [small molecule metabolic process]
GO:0071377 [cellular response to glucagon stimulus]
GO:0097481 [neuronal postsynaptic density]
Show all
 75 aa
8.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.