Expression of BEND5 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

BEND5

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	BEND5
Gene description	BEN domain containing 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (AF22, HDLM-2, MOLT-4, REH, SH-SY5Y)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA054347 , HPA058007
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable), breast cancer (favourable), pancreatic cancer (favourable) and lung cancer (favourable).
Urothelial cancer p<0.001 Breast cancer p<0.001 Pancreatic cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA054347	HPA058007

GENE INFORMATION
Gene name	BEND5 (HGNC Symbol)
Synonyms	C1orf165, FLJ11588
Description	BEN domain containing 5 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p33
Chromosome location (bp)	48727523 - 48776969
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162373 (version 83.38)
Entrez gene	79656
UniProt	Q7L4P6 (UniProt - Evidence at protein level)
neXtProt	NX_Q7L4P6
Antibodypedia	BEND5 antibodies

PROTEIN BROWSER

BEND5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BEND5-001 ENSP00000360899 ENST00000371833	Q7L4P6 [Direct mapping] BEN domain-containing protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005794 [Golgi apparatus] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	421 aa 48.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.