Expression of COA7 in cancer - Summary - The Human Protein Atlas

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COA7

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	COA7
Gene description	Cytochrome c oxidase assembly factor 7 (putative)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 2 antibodies. HPA028154 , HPA029926
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable), stomach cancer (favourable) and endometrial cancer (unfavourable).
Liver cancer p<0.001 Stomach cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028154	HPA029926

GENE INFORMATION
Gene name	COA7 (HGNC Symbol)
Synonyms	C1orf163, FLJ12439, RESA1, SELRC1
Description	Cytochrome c oxidase assembly factor 7 (putative) (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	52684451 - 52698366
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162377 (version 83.38)
Entrez gene	65260
UniProt	Q96BR5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BR5
Antibodypedia	COA7 antibodies

PROTEIN BROWSER

COA7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COA7-001 ENSP00000360593 ENST00000371538	Q96BR5 [Direct mapping] Cytochrome c oxidase assembly factor 7 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005758 [mitochondrial intermembrane space] Show all	231 aa 25.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.