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TSSK3

GENERAL INFORMATION

Gene name

 TSSK3

Gene description

 Testis-specific serine kinase 3

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Mixed
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA037516
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037516

GENE INFORMATION

Gene name

 TSSK3 (HGNC Symbol)

Synonyms

 SPOGA3, STK22C

Description

 Testis-specific serine kinase 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008]

Chromosome

 1

Cytoband

 p35.1

Chromosome location (bp)

 32351521 - 32364312

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162526 (version 83.38)

Entrez gene

 81629

UniProt

 Q96PN8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96PN8

Antibodypedia

 TSSK3 antibodies

PROTEIN BROWSER
TSSK3-001
TSSK3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TSSK3-001
ENSP00000362634
ENST00000373534
Q96PN8 [Direct mapping]
Testis-specific serine/threonine-protein kinase 3
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
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GO:0000287 [magnesium ion binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0030154 [cell differentiation]
GO:0035556 [intracellular signal transduction]
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 268 aa
30.1 kDa 		No 0
TSSK3-002
ENSP00000459187
ENST00000574315
I3L1X4 [Direct mapping]
Testis-specific serine/threonine-protein kinase 3
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Predicted intracellular proteins
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GO:0004674 [protein serine/threonine kinase activity]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0035556 [intracellular signal transduction]
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 35 aa
3.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.