Expression of OLFML2B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

OLFML2B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OLFML2B
Gene description	Olfactomedin-like 2B
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (ASC TERT1, RH-30, U-87 MG)
HPA (normal tissue):	Tissue enhanced (gallbladder)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Approved based on 1 antibody. HPA054136
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA054136

GENE INFORMATION
Gene name	OLFML2B (HGNC Symbol)
Synonyms	DKFZP586L151
Description	Olfactomedin-like 2B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q23.3
Chromosome location (bp)	161983192 - 162023854
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162745 (version 83.38)
Entrez gene	25903
UniProt	Q68BL8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q68BL8
Antibodypedia	OLFML2B antibodies

PROTEIN BROWSER

OLFML2B-001	OLFML2B-002	OLFML2B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OLFML2B-001 ENSP00000294794 ENST00000294794	Q68BL8 [Direct mapping] Olfactomedin-like protein 2B Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] Show all	750 aa 84 kDa	Yes	0
OLFML2B-002 ENSP00000356915 ENST00000367938	Q68BL8 [Direct mapping] Olfactomedin-like protein 2B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] Show all	233 aa 27.6 kDa	No	0
OLFML2B-006 ENSP00000356917 ENST00000367940	F2Z3N3 [Direct mapping] Olfactomedin-like protein 2B Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005578 [proteinaceous extracellular matrix] GO:0030198 [extracellular matrix organization] GO:0050840 [extracellular matrix binding] Show all	751 aa 84.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.