Expression of SNED1 in cancer - Summary - The Human Protein Atlas

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SNED1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SNED1
Gene description	Sushi, nidogen and EGF-like domains 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (ASC TERT1)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic and membranous expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA036414 , HPA036415
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036414	HPA036415

GENE INFORMATION
Gene name	SNED1 (HGNC Symbol)
Synonyms	FLJ00133, Snep, SST3
Description	Sushi, nidogen and EGF-like domains 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q37.3
Chromosome location (bp)	240998838 - 241095568
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162804 (version 83.38)
Entrez gene	25992
UniProt	Q8TER0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TER0
Antibodypedia	SNED1 antibodies

PROTEIN BROWSER

SNED1-001	SNED1-004	SNED1-005	SNED1-008	SNED1-009	SNED1-013	SNED1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNED1-001 ENSP00000308893 ENST00000310397	Q8TER0 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0007160 [cell-matrix adhesion] GO:0070062 [extracellular exosome] Show all	1413 aa 152.2 kDa	Yes	0
SNED1-004 ENSP00000386007 ENST00000405547	Q8TER0 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0007160 [cell-matrix adhesion] GO:0070062 [extracellular exosome] Show all	1352 aa 145.3 kDa	Yes	0
SNED1-005 ENSP00000384871 ENST00000401884	Q8TER0 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0007160 [cell-matrix adhesion] GO:0070062 [extracellular exosome] Show all	1324 aa 142.1 kDa	Yes	0
SNED1-008 ENSP00000384789 ENST00000401644	H7BYY9 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	300 aa 31.4 kDa	No	0
SNED1-009 ENSP00000401865 ENST00000431690	H7C1R9 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	272 aa 28.4 kDa	No	0
SNED1-013 ENSP00000394324 ENST00000420591	H7C0D4 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	66 aa 6.8 kDa	No	0
SNED1-201 ENSP00000342992 ENST00000342631	B5MEF5 [Direct mapping] Sushi, nidogen and EGF-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] Show all	599 aa 65.2 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.