We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Most malignancies were negative. A majority of malignant carcinoids showed moderate nuclear positivity.
GENE INFORMATION
Gene name
NEUROD1 (HGNC Symbol)
Synonyms
BETA2, BHF-1, bHLHa3, MODY6, NEUROD
Description
Neuronal differentiation 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008]