Expression of CLHC1 in cancer - Summary - The Human Protein Atlas

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CLHC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CLHC1
Gene description	Clathrin heavy chain linker domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA045418
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045418

GENE INFORMATION
Gene name	CLHC1 (HGNC Symbol)
Synonyms	C2orf63, FLJ31438
Description	Clathrin heavy chain linker domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p16.1
Chromosome location (bp)	55174791 - 55232563
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162994 (version 83.38)
Entrez gene	130162
UniProt	Q8NHS4 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NHS4
Antibodypedia	CLHC1 antibodies

PROTEIN BROWSER

CLHC1-002	CLHC1-003	CLHC1-004	CLHC1-012	CLHC1-013	CLHC1-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLHC1-002 ENSP00000385778 ENST00000407122	Q8NHS4 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	586 aa 67.2 kDa	No	0
CLHC1-003 ENSP00000385512 ENST00000406076	Q8NHS4 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	464 aa 53 kDa	No	0
CLHC1-004 ENSP00000384869 ENST00000401408	Q8NHS4 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005488 [binding] GO:0005515 [protein binding] Show all	586 aa 67.2 kDa	No	0
CLHC1-012 ENSP00000400116 ENST00000425841	C9J143 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all		17 aa 1.9 kDa	No	0
CLHC1-013 ENSP00000385598 ENST00000403506	B5MC48 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all		46 aa 5.3 kDa	No	0
CLHC1-014 ENSP00000407575 ENST00000451916	E7EVC5 [Direct mapping] Clathrin heavy chain linker domain-containing protein 1 Show all	Predicted intracellular proteins Show all		80 aa 9.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.