Expression of CCDC74A in cancer - Summary - The Human Protein Atlas

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CCDC74A

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	CCDC74A
Gene description	Coiled-coil domain containing 74A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (NTERA-2, SCLC-21H)
HPA (normal tissue):	Tissue enhanced (fallopian tube, testis)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), glioma (unfavourable), testis cancer (favourable) and breast cancer (favourable).
Renal cancer p<0.001 Glioma p<0.001 Testis cancer p<0.001 Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	CCDC74A (HGNC Symbol)
Synonyms	FLJ40345
Description	Coiled-coil domain containing 74A (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q21.1
Chromosome location (bp)	131527675 - 131533666
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000163040 (version 83.38)
Entrez gene	90557
UniProt	Q96AQ1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96AQ1
Antibodypedia	CCDC74A antibodies

PROTEIN BROWSER

CCDC74A-001	CCDC74A-002	CCDC74A-009	CCDC74A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC74A-001 ENSP00000295171 ENST00000295171	Q96AQ1 [Direct mapping] Coiled-coil domain-containing protein 74A Show all	Predicted intracellular proteins Show all		378 aa 41.6 kDa	No	0
CCDC74A-002 ENSP00000387009 ENST00000409856	Q96AQ1 [Direct mapping] Coiled-coil domain-containing protein 74A Show all	Predicted intracellular proteins Show all		312 aa 34.9 kDa	No	0
CCDC74A-009 ENSP00000406839 ENST00000434330	C9IYK9 [Direct mapping] Coiled-coil domain-containing protein 74A Show all	Predicted intracellular proteins Show all		206 aa 21.9 kDa	No	0
CCDC74A-201 ENSP00000444610 ENST00000467992	F5GZA4 [Direct mapping] Coiled-coil domain-containing protein 74A Show all	Predicted intracellular proteins Show all		272 aa 29.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.