Cell atlas - SGPP2 - The Human Protein Atlas

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SGPP2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SGPP2
Gene description	Sphingosine-1-phosphate phosphatase 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (RPTEC TERT1, hTCEpi, SCLC-21H, CAPAN-2)
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RPTEC TERT1, hTCEpi, SCLC-21H, CAPAN-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SGPP2 (HGNC Symbol)
Synonyms	FLJ39004, SPP2
Description	Sphingosine-1-phosphate phosphatase 2 (HGNC Symbol)
Entrez gene summary	Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P (Ogawa et al., 2003 [PubMed 12411432]).[supplied by OMIM, Jun 2009]
Chromosome	2
Cytoband	q36.1
Chromosome location (bp)	222424517 - 222560948
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000163082 (version 83.38)
Entrez gene	130367
UniProt	Q8IWX5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IWX5
Antibodypedia	SGPP2 antibodies

PROTEIN BROWSER

SGPP2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SGPP2-001 ENSP00000315137 ENST00000321276	Q8IWX5 [Direct mapping] Sphingosine-1-phosphate phosphatase 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006665 [sphingolipid metabolic process] GO:0006670 [sphingosine metabolic process] GO:0016021 [integral component of membrane] GO:0016311 [dephosphorylation] GO:0030148 [sphingolipid biosynthetic process] GO:0042392 [sphingosine-1-phosphate phosphatase activity] GO:0044281 [small molecule metabolic process] Show all	399 aa 44.7 kDa	No	9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.