Expression of C1orf189 in cancer - Summary

GENERAL INFORMATION
Gene name	C1orf189
Gene description	Chromosome 1 open reading frame 189
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Mixed
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Luminal membranous expression in several tissues, including fallopian tube and renal tubules.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA045779
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

STAINING SUMMARY

HPA045779

GENE INFORMATION
Gene name	C1orf189
Synonyms
Description	Chromosome 1 open reading frame 189 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	154199372 - 154206333
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163263 (version 83.38)
Entrez gene	388701
UniProt	Q5VU69 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VU69
Antibodypedia	C1orf189 antibodies

PROTEIN BROWSER

C1orf189-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C1orf189-001 ENSP00000357511 ENST00000368525	Q5VU69 [Direct mapping] Uncharacterized protein C1orf189 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	101 aa 12.1 kDa	No	0